All Course: Long Term fellowship Program

• What is Infertility
• Embryology of female genital tract
• Anatomy of female Genital tract
• Hormones in reproduction:
  • Role of Estrogen
  • Role of Progesterone
  • Role of FSH
  • Role of LH
  • Role of AMH
• Pituitary hypothallamo ovarian axis
• Patient counselling
• Physiology of Ovulation
• Causes of Infertility – diagnosis
• Anovulation – definition
  • Types
  • Causes
  • Treatment of each
• Polycytsic ovarian diseases – pathophysiology
  • Diagnosis in adolescent & in adult
  • Hormonal parameter
  • Ultrasound
  • Metabolic component
  • Management strategies – depending on the aim of treatment
  • 2018 ESHRE consensus and guidelines for diagnosis and treatment of PCOS
• Poor Ovarian reserve
  • Causes
  • Bologna criteria
  • Diagnosis
  • Management strategies
  • Assessment of ovarian reserve – different tests accuracy
  • Practical importance

Uterine causes of infertility

• Congenital uterine anomalies:
  • diagnosis
  • Treatment of strategies
  • Outcome of pregnancy
• Uterine pathologies and fertility prognosis

Tubal cause of Infertility

• Causes
• Diagnosis
• Pregnancy prognosis
• Management

Cervical causes of Infertility

• What is the importance
• Does it exist in presence of ART?

Ovulation induction methods For IUI /For IVF

• Oral ovulogens
• Different gonadotrophin protocols
• Role of down regulators
• Agonist/ Antagonist
• Role of LH in ovulation Induction
• Role of progesterone in ovulation induction
• Luteal phase assessment
  • Abnormal luteal phase
  • Causes
  • Management
• Ovulation Trigger – hCG/agonist

Implantation:

• Physiology of implantation
• Causes of implantation failure
• Recurrent implantation failure
• Investigations & diagnosis
• Management strategies
• New endometrial receptivity tests

IUI – Intra uterine insemination

• Indication
• Success rates – present results
• Optimising results

Male factors of Infertility

• Spermatogenesis – physiology
• Anatomy of male reproductive tract
• Hormonal assessment
• Normal semen parameters
• Abnormal semen parameters
• Causes of oligoasthenospermia & teratozoospermia
• Treating abnormal sperm parameters
• Surgical treatment of male Infertility – PESA/TESA, Varicoccoelectomy, surgical techniques for obstructive azoospermia
• Medical management of male infertility
• Genetic factor of male infertility

IVF – In vitro Fertilization

• Clinical aspects
• Anaesthesia
• Ovum pickup
  • Method
  • Variation
  • Complication
• Embryo Transfer
  • Method
  • Alternatives – mock transfer, catheter types, ultrasound guidance
  • Change in results
  • Complication

Embryology aspects of IVF

• Embryo development
• Gamete handling techniques
• IVF
• ICSI
• Assisted Hatching
• IMSI
• Segmentation of IVF
• Genetics in Infertility
• Role of stem cells in reproduction
• Newer methods – mitochondrial transfer
  • Stem cell in infertility
  • Ovarian regenesis
  • Endometrial regenesis
  • PRP
  • GCSF

Setting up IUI Laboratory

• Setting up IVF laboratory – about the instruments – choices
• Maintenance of the IVF & IUI lab equipment
• Cleansing of IUI lab/IVF lab – maintenance
• Role of Ultrasound in Infertility Management
  • For dose decision
  • For trigger , Timing of IUI
  • Luteal phase assessment
• Ovarian hyper stimulation syndrome
  • Diagnosis
  • Monitoring
  • Treatment protocols