Curriculum for the observership course in Infertility & IVF- 3 month

  • What is Infertility
  • Anatomy of the female genital tract
  • Hormones in reproduction:
    • Role of Estrogen
    • Role of Progesterone
    • Role of FSH
    • Role of LH
  • Role of AMH
  • Pituitary hypothalamic ovarian axis
  • Patient counseling
  • Physiology of Ovulation
  • Causes of Infertility – diagnosis
  • Anovulation – definition
    • Types
    • Causes
    • Treatment of each
  • Polycystic ovarian diseases – pathophysiology
    • Diagnosis in adolescent & in adult
    • Hormonal parameter
    • Ultrasound
    • Metabolic component
    • Management strategies – depending on the aim of treatment
    • 2018 ESHRE consensus and guidelines for diagnosis and treatment of PCOS
  • Poor Ovarian reserve
    • Causes
    • Bologna criteria
    • Diagnosis
    • Management strategies
    • Assessment of ovarian reserve

Uterine causes of infertility

  • Congenital uterine anomalies:
    • Diagnosis
    • Treatment of strategies
  • Uterine pathologies and fertility prognosis

Tubal cause of Infertility

  • Diagnosis
  • Management

Cervical causes of Infertility

  • What is the importance
  • Does it exist in the presence of ART?

Ovulation induction methods For IUI /For IVF

  • Oral ovulogens
  • Different gonadotrophin protocols
  • Role of down regulators
  • Agonist/ Antagonist
  • Role of LH in ovulation Induction
  • Role of progesterone in ovulation induction
  • Luteal phase assessment
    • Abnormal luteal phase
    • Causes
    • Management

Ovulation Trigger – hCG/agonist

Implantation: – Physiology of implantation

  • Causes of implantation failure
  • Recurrent implantation failure
  • Investigations & diagnosis
  • Management strategies
  • New endometrial receptivity tests

IUI – Intra uterine insemination

  • Indication
  • Success rates – present results
  • Optimizing results

Male factors of Infertility

  • Anatomy of the male reproductive tract
  • Hormonal assessment
  • Normal semen parameters
  • Abnormal semen parameters
  • Causes of oligoasthenospermia & teratozoospermia
  • Treating abnormal sperm parameters
  • Medical management of male infertility

IVF – In-vitro Fertilization

  • Clinical aspects
  • Anesthesia
  • Ovum pickup
    • Method
    • Variation
    • Complication
  • Embryo Transfer
    • Method
    • Alternatives – mock transfer, catheter types, ultrasound guidance
    • Change in results
    • Complication

Embryology aspects of IVF

  • Embryo development
  • Gamete handling techniques
  • IVF
  • ICSI
  • Assisted Hatching
  • IMSI
  • Segmentation of IVF

Setting up IUI & IVF Laboratory

  • Setting up IVF laboratory – about the instruments – choices
  • Maintenance of the IVF & IUI lab equipment
  • Role of Ultrasound in Infertility Management
    • For dose decision
    • For the trigger, Timing of IUI
    • Luteal phase assessment
  • Ovarian hyperstimulation syndrome
    • Diagnosis
    • Monitoring
    • Treatment protocols
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