Curriculum for the observership course in Infertility & IVF- 3 month
- What is Infertility
- Anatomy of the female genital tract
- Hormones in reproduction:
- Role of Estrogen
- Role of Progesterone
- Role of FSH
- Role of LH
- Role of AMH
- Pituitary hypothalamic ovarian axis
- Patient counseling
- Physiology of Ovulation
- Causes of Infertility – diagnosis
- Anovulation – definition
- Types
- Causes
- Treatment of each
- Polycystic ovarian diseases – pathophysiology
- Diagnosis in adolescent & in adult
- Hormonal parameter
- Ultrasound
- Metabolic component
- Management strategies – depending on the aim of treatment
- 2018 ESHRE consensus and guidelines for diagnosis and treatment of PCOS
- Poor Ovarian reserve
- Causes
- Bologna criteria
- Diagnosis
- Management strategies
- Assessment of ovarian reserve
Uterine causes of infertility
- Congenital uterine anomalies:
- Diagnosis
- Treatment of strategies
- Uterine pathologies and fertility prognosis
Tubal cause of Infertility
- Diagnosis
- Management
Cervical causes of Infertility
- What is the importance
- Does it exist in the presence of ART?
Ovulation induction methods For IUI /For IVF
- Oral ovulogens
- Different gonadotrophin protocols
- Role of down regulators
- Agonist/ Antagonist
- Role of LH in ovulation Induction
- Role of progesterone in ovulation induction
- Luteal phase assessment
- Abnormal luteal phase
- Causes
- Management
Ovulation Trigger – hCG/agonist
Implantation: – Physiology of implantation
- Causes of implantation failure
- Recurrent implantation failure
- Investigations & diagnosis
- Management strategies
- New endometrial receptivity tests
IUI – Intra uterine insemination
- Indication
- Success rates – present results
- Optimizing results
Male factors of Infertility
- Anatomy of the male reproductive tract
- Hormonal assessment
- Normal semen parameters
- Abnormal semen parameters
- Causes of oligoasthenospermia & teratozoospermia
- Treating abnormal sperm parameters
- Medical management of male infertility
IVF – In-vitro Fertilization
- Clinical aspects
- Anesthesia
- Ovum pickup
- Method
- Variation
- Complication
- Embryo Transfer
- Method
- Alternatives – mock transfer, catheter types, ultrasound guidance
- Change in results
- Complication
Embryology aspects of IVF
- Embryo development
- Gamete handling techniques
- IVF
- ICSI
- Assisted Hatching
- IMSI
- Segmentation of IVF
Setting up IUI & IVF Laboratory
- Setting up IVF laboratory – about the instruments – choices
- Maintenance of the IVF & IUI lab equipment
- Role of Ultrasound in Infertility Management
- For dose decision
- For the trigger, Timing of IUI
- Luteal phase assessment
- Ovarian hyperstimulation syndrome
- Diagnosis
- Monitoring
- Treatment protocols
